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Kiss, Katalin É

Population-based studies show that atherosclerosis, the major precursor of cardiovascular disease, begins in childhood. The Pathobiological Determinants of Atherosclerosis in Youth PDAY study demonstrated that intimal lesions appear in all the aortas and more than half of the right coronary arteries of youths aged 7—9 years.

This is extremely important considering that 1 in 3 people die from complications attributable to atherosclerosis. In order to stem the tide, education and awareness that cardiovascular disease poses the greatest threat, and measures to prevent or reverse this disease must be taken. Obesity and diabetes mellitus are often linked to cardiovascular disease, [66] as are a history of chronic kidney disease and hypercholesterolaemia. Screening ECGs either at rest or with exercise are not recommended in those without symptoms who are at low risk. The NIH recommends lipid testing in children beginning at the age of 2 if there is a family history of heart disease or lipid problems.

Screening and selection for primary prevention interventions has traditionally been done through absolute risk using a variety of scores ex. Framingham or Reynolds risk scores.


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The number and variety of risk scores available for use has multiplied, but their efficacy according to a review was unclear due to lack of external validation or impact analysis. Most guidelines recommend combining preventive strategies. A Cochrane Review found some evidence that interventions aiming to reduce more than one cardiovascular risk factor may have beneficial effects on blood pressure, body mass index and waist circumference; however, evidence was limited and the authors were unable to draw firm conclusions on the effects on cardiovascular events and mortality.

It is unclear whether or not dental care in those with periodontitis affects their risk of cardiovascular disease. A diet high in fruits and vegetables decreases the risk of cardiovascular disease and death. Total fat intake does not appear to be an important risk factor. A Cochrane review found unclear benefit of recommending a low-salt diet in people with high or normal blood pressure. Blood pressure medication reduces cardiovascular disease in people at risk, [94] irrespective of age, [] the baseline level of cardiovascular risk, [] or baseline blood pressure.

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Statins are effective in preventing further cardiovascular disease in people with a history of cardiovascular disease. Anti-diabetic medication may reduce cardiovascular risk in people with Type 2 Diabetes, although evidence is not conclusive. Aspirin has been found to be of only modest benefit in those at low risk of heart disease as the risk of serious bleeding is almost equal to the benefit with respect to cardiovascular problems.

The use of vasoactive agents for people with pulmonary hypertension with left heart disease or hypoxemic lung diseases may cause harm and unnecessary expense.

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Exercise-based cardiac rehabilitation following a heart attack reduces the risk of death from cardiovascular disease and leads to less hospitalizations. A Cochrane review found some evidence that yoga has beneficial effects on blood pressure and cholesterol, but studies included in this review were of low quality.

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While a healthy diet is beneficial, the effect of antioxidant supplementation vitamin E , vitamin C , etc. Cardiovascular disease is treatable with initial treatment primarily focused on diet and lifestyle interventions. Proper CVD management necessitates a focus on MI and stroke cases due to their combined high mortality rate, keeping in mind the cost-effectiveness of any intervention, especially in developing countries with low or middle income levels. Cardiovascular diseases are the leading cause of death worldwide and in all regions except Africa. It is also estimated that by , over 23 million people will die from cardiovascular diseases each year.

This may be secondary to a combination of genetic predisposition and environmental factors.


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  • Organizations such as the Indian Heart Association are working with the World Heart Federation to raise awareness about this issue. There is evidence that cardiovascular disease existed in pre-history, [] and research into cardiovascular disease dates from at least the 18th century. Recent areas of research include the link between inflammation and atherosclerosis [] the potential for novel therapeutic interventions, [] and the genetics of coronary heart disease. From Wikipedia, the free encyclopedia. Cardiovascular disease Micrograph of a heart with fibrosis yellow and amyloidosis brown.

    Movat's stain. Specialty Cardiology Usual onset Older adults [1] Types Coronary artery diseases , stroke , heart failure , hypertensive heart disease , rheumatic heart disease , cardiomyopathy [2] [3] Prevention Healthy eating , exercise, avoiding tobacco smoke, limited alcohol intake [2] Treatment Treating high blood pressure , high blood lipids , diabetes [2] Deaths Main article: Occupational cardiovascular disease.

    See also: Saturated fat and cardiovascular disease and Salt and cardiovascular disease. See also: Timeline of cardiovascular disease. January Archived PDF from the original on August The Cochrane Database of Systematic Reviews. Bibcode : PLoSO September Health Technology Assessment. Archived from the original on Global atlas on cardiovascular disease prevention and control 1 ed. World Health Organization. Retrieved Nov 11, Current Atherosclerosis Reports. World Journal of Cardiology Review. October Nature Genetics. International Journal of Cardiology.

    International Journal of Endocrinology. American Heart Association. The Atlas of Heart Disease and Stroke.

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    Postgraduate Medical Journal. Retrieved May 22, Archived from the original on May 23, Retrieved May 23, Sex difference in ischaemic heart disease mortality and risk factors in 46 communities: an ecologic analysis. Cardiovasc Risk Factors. Prevention of Cardiovascular Disease.

    Heart Failure

    Archived from the original on 27 April Nutrition, Metabolism, and Cardiovascular Diseases. Journal of the American Dietetic Association. Retrieved 15 May The American Journal of Clinical Nutrition. Journal of the American College of Cardiology.

    Event structure and the left periphery : studies on Hungarian - Semantic Scholar

    Global Status Report on Alcohol and Health. Circulation Review. February Translation techniques revisited: a dynamic and functionalist approach. Participiul rezultativ-predicativ. An aspectual view]. Orwell George. The Acquisition of the English passive construction by L1 speakers of Hungarian. PhD thesis. Bucharest: University of Bucharest. L2 romanian influence in the acquisition of the English passive by L1 speakers of Hungarian. Acta Universitatis Sapientiae Philologica 6 2 : — Approaches to Hungarian 7: — Home About us Subjects Contacts.

    Advanced Search Help. Entire Site De Gruyter Online. Sign in Register. English Deutsch. Open access. In prep. Acta Linguistica Hungarica, 63 2. Free Choice and Aspect in Hungarian. Approaches to Hungarian. Volume Papers from the Piliscsaba Conference.

    John Benjamins Publishing Company, Amsterdam, The morphosyntactic encoding of middle voice anticausatives, dispositional middles, reflexives, reciprocals and antipassives has changed radically in the history of Hungarian. I am looking at how this can inform our cross-linguistic generalizations about the mechanisms underlying grammaticalization.